HESI A2 Anatomy and Physiology 2025 – 400 Free Practice Questions to Pass the Exam

The liver is the primary organ responsible for the detoxification of blood in the body. It performs this essential function by metabolizing various substances, including drugs, alcohol, and toxins, converting them into less harmful compounds that can be excreted from the body. The liver accomplishes this through a series of biochemical reactions, which can involve oxidation, reduction, hydrolysis, and conjugation.

Additionally, the liver produces important proteins that are crucial for blood clotting and synthesis of biochemicals necessary for digestion. It filters out toxins and waste products that arise from metabolism, ensuring that these do not accumulate in the blood and cause harm to other organs.

While the kidneys also play a significant role in filtering blood by removing waste products and excess substances, their main function is the excretion of urine rather than detoxification. The pancreas is involved in digestion and blood sugar regulation, while the gallbladder primarily stores bile produced by the liver, which aids in the digestion of fats.